What supplements does Bryan Johnson take?

Bryan Johnson takes over 100 supplements daily as part of his Blueprint protocol. The core stack available to the public includes Essential Capsules (24 nutrients), Longevity Mix, Omega-3, Collagen Peptides, and Extra Virgin Olive Oil. These are third-party tested and formulated at clinically-studied doses.

What is the Blueprint protocol?

The Blueprint protocol is Bryan Johnson's comprehensive anti-aging and longevity regimen. It combines diet, exercise, sleep optimization, and science-backed supplements to reverse biological age. Johnson has spent over $4 million researching and measuring 70+ organs to develop this protocol.

Are Blueprint supplements worth it?

Blueprint supplements use premium, bioavailable ingredients at clinically-effective doses, unlike drugstore vitamins that often use "pixie dusting" (ineffective amounts). Every batch is third-party tested for purity and heavy metals. While more expensive than generic supplements, they provide superior quality and transparency.

How long until I see results from Blueprint supplements?

Many users report improved energy and sleep within 2-4 weeks of starting Blueprint supplements. However, the deeper cellular benefits that affect biological age build over months. Bryan Johnson recommends committing to at least 90 days for optimal results.

Can supplements actually reverse biological age?

Research shows that certain supplements combined with lifestyle changes can reduce biological age. Studies have demonstrated 4-5 year reductions in biological age over 8-16 weeks with proper supplementation including vitamin D, NMN, and omega-3s, alongside diet and exercise optimization.

2026 Comparison Guide

Blueprint vs Thorne

Bryan Johnson's curated longevity stack versus Thorne's practitioner-grade supplements. Two premium approaches to supplementation.

Quick Verdict

Blueprint wins 1 categories, Thorne wins 5.

Both are premium options. Blueprint wins for those who want a curated, longevity-focused stack without the research required to build your own regimen. Thorne wins for those who want maximum customization, practitioner guidance, or NSF sport certification.

Try Blueprint ($25 Off)

Detailed Comparison

Category	Blueprint	Thorne
Brand Heritage	Founded by Bryan Johnson (tech entrepreneur)	✓40+ years in practitioner-grade supplements
Primary Focus	Longevity & biological age reversal	Practitioner-grade individual supplements
Product Range	5 curated products for longevity	✓100+ individual supplements
NMN Availability	Included in Longevity Mix	NMN available separately (NiaCel 400)
Formulation Approach	All-in-one longevity stacks	Individual supplements, mix & match
Third-Party Testing	Every batch, COAs published	NSF Certified for Sport, extensive testing
Price Point	$39-72 per product	$20-80+ per product
Ease of Use	✓Curated stack, simple routine	Requires research to build your own stack
Practitioner Access	Direct to consumer	✓Available through healthcare practitioners
Research Investment	$4M+ personal biological age research	Extensive clinical research partnerships
Bioavailability Focus	Optimized forms included	✓Known for superior bioavailable forms
Athlete Certification	Not NSF Certified for Sport	✓NSF Certified for Sport (many products)

Strengths of Each

Blueprint Strengths

✓Curated longevity stack - no guesswork required
✓Based on Bryan Johnson's measured age reversal results
✓Simplified routine with products designed to work together
✓NMN included in base Longevity Mix formula
✓Direct to consumer with $25 first-order discount
✓Specifically optimized for biological age reversal

Thorne Strengths

✓40+ years of industry experience and trust
✓NSF Certified for Sport - trusted by athletes
✓Massive product range for customization
✓Available through healthcare practitioners
✓Industry leader in bioavailable ingredient forms
✓Extensive research partnerships with institutions

Which Should You Choose?

Choose Blueprint if:

You want a ready-made longevity stack based on Bryan Johnson's biological age research. You prefer simplicity and don't want to research individual supplements. You're focused specifically on anti-aging.

Choose Thorne if:

You want to build a custom supplement stack with practitioner guidance. You're an athlete needing NSF certification. You prefer a brand with 40+ years of industry trust.

Ready to Optimize for Longevity?

Try Bryan Johnson's Blueprint supplements and get $25 off your first order. Third-party tested with published certificates of analysis.

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Learn more:

Is Blueprint Worth It?Bryan Johnson Supplement List Best NMN Supplements FAQ

Other comparisons:

Blueprint vs AG1 Blueprint vs Athletic Greens Blueprint vs Seed Blueprint vs Ritual Blueprint vs Thorne Blueprint vs Momentous Blueprint vs Life Extension Blueprint vs Generic NMN