What supplements does Bryan Johnson take?

Bryan Johnson takes over 100 supplements daily as part of his Blueprint protocol. The core stack available to the public includes Essential Capsules (24 nutrients), Longevity Mix, Omega-3, Collagen Peptides, and Extra Virgin Olive Oil. These are third-party tested and formulated at clinically-studied doses.

What is the Blueprint protocol?

The Blueprint protocol is Bryan Johnson's comprehensive anti-aging and longevity regimen. It combines diet, exercise, sleep optimization, and science-backed supplements to reverse biological age. Johnson has spent over $4 million researching and measuring 70+ organs to develop this protocol.

Are Blueprint supplements worth it?

Blueprint supplements use premium, bioavailable ingredients at clinically-effective doses, unlike drugstore vitamins that often use "pixie dusting" (ineffective amounts). Every batch is third-party tested for purity and heavy metals. While more expensive than generic supplements, they provide superior quality and transparency.

How long until I see results from Blueprint supplements?

Many users report improved energy and sleep within 2-4 weeks of starting Blueprint supplements. However, the deeper cellular benefits that affect biological age build over months. Bryan Johnson recommends committing to at least 90 days for optimal results.

Can supplements actually reverse biological age?

Research shows that certain supplements combined with lifestyle changes can reduce biological age. Studies have demonstrated 4-5 year reductions in biological age over 8-16 weeks with proper supplementation including vitamin D, NMN, and omega-3s, alongside diet and exercise optimization.

2026 Comparison Guide

Blueprint vs Life Extension

Two leading longevity supplement approaches: Bryan Johnson's curated stack vs Life Extension's extensive catalog. Which is right for you?

Quick Verdict

Blueprint wins 4 categories, Life Extension wins 2.

Blueprint wins for simplicity and proven biological age results. Life Extension wins for those who want maximum customization and already know exactly what they need.

Try Blueprint ($25 Off)

Detailed Comparison

Category	Blueprint	Life Extension
Brand Focus	Bryan Johnson's personal longevity protocol	Broad supplement catalog (400+ products)
Curation	✓Curated stack based on biological age data	DIY - choose from hundreds of options
NMN Quality	Included in Longevity Mix, tested	Separate NMN product available
Testing Standards	Every batch third-party tested, COAs public	Third-party tested, COAs available
Simplicity	✓5-product curated system	Must research and choose from 400+ products
Ingredient Dosing	Clinical doses, fully transparent	Generally clinical doses, transparent
Price (Full Stack)	✓~$265/month for complete protocol	$300-500/month for comparable stack
Product Range	Focused on core longevity needs	✓Extensive catalog for specific needs
Scientific Backing	✓Based on measured biological age outcomes	Based on published research
Customization	Pre-designed optimal stack	✓Highly customizable

Strengths of Each

Blueprint Strengths

✓Curated stack removes guesswork from supplementation
✓Based on Bryan Johnson's actual biological age reversal results
✓More cost-effective than building comparable Life Extension stack
✓Synergistic formulations designed to work together
✓Simplified protocol - just 5 core products

Life Extension Strengths

✓Massive product selection for specific needs
✓Long-established reputation in longevity space
✓Highly customizable for individual protocols
✓Often has sales and discount programs
✓Extensive educational resources and research

Which Should You Choose?

Choose Blueprint if:

You want a proven, curated longevity stack without the research overhead. You trust Bryan Johnson's biological age data and want a simplified protocol.

Choose Life Extension if:

You're an experienced biohacker who wants to build a highly customized stack, or you need specific supplements Life Extension offers that Blueprint doesn't.

Ready to Optimize for Longevity?

Try Bryan Johnson's Blueprint supplements and get $25 off your first order. Third-party tested with published certificates of analysis.

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Learn more:

Is Blueprint Worth It?Bryan Johnson Supplement List Best NMN Supplements FAQ

Other comparisons:

Blueprint vs AG1 Blueprint vs Athletic Greens Blueprint vs Seed Blueprint vs Ritual Blueprint vs Thorne Blueprint vs Momentous Blueprint vs Life Extension Blueprint vs Generic NMN