What supplements does Bryan Johnson take?

Bryan Johnson takes over 100 supplements daily as part of his Blueprint protocol. The core stack available to the public includes Essential Capsules (24 nutrients), Longevity Mix, Omega-3, Collagen Peptides, and Extra Virgin Olive Oil. These are third-party tested and formulated at clinically-studied doses.

What is the Blueprint protocol?

The Blueprint protocol is Bryan Johnson's comprehensive anti-aging and longevity regimen. It combines diet, exercise, sleep optimization, and science-backed supplements to reverse biological age. Johnson has spent over $4 million researching and measuring 70+ organs to develop this protocol.

Are Blueprint supplements worth it?

Blueprint supplements use premium, bioavailable ingredients at clinically-effective doses, unlike drugstore vitamins that often use "pixie dusting" (ineffective amounts). Every batch is third-party tested for purity and heavy metals. While more expensive than generic supplements, they provide superior quality and transparency.

How long until I see results from Blueprint supplements?

Many users report improved energy and sleep within 2-4 weeks of starting Blueprint supplements. However, the deeper cellular benefits that affect biological age build over months. Bryan Johnson recommends committing to at least 90 days for optimal results.

Can supplements actually reverse biological age?

Research shows that certain supplements combined with lifestyle changes can reduce biological age. Studies have demonstrated 4-5 year reductions in biological age over 8-16 weeks with proper supplementation including vitamin D, NMN, and omega-3s, alongside diet and exercise optimization.

2026 Comparison Guide

Blueprint vs Seed

Comparing Bryan Johnson's longevity stack with Seed's premium probiotic. Which supplement approach is right for your health goals?

Quick Verdict

Blueprint wins 5 categories, Seed wins 5.

Blueprint is the better choice for comprehensive longevity optimization, while Seed excels specifically at gut health. If you're focused on anti-aging and biological age reversal, Blueprint's NMN and multi-system approach wins. If gut health is your primary concern, Seed's specialized probiotic formula is excellent.

Try Blueprint ($25 Off)

Detailed Comparison

Category	Blueprint	Seed
Primary Focus	Comprehensive longevity & biological age reversal	Gut health & probiotics
Product Range	✓5 products covering full-spectrum health	Single product (Daily Synbiotic)
NMN/NAD+ Support	✓Yes - clinically-dosed NMN in Longevity Mix	No NAD+ precursors
Probiotic Strains	Not a primary focus	✓24 clinically-studied strains
Prebiotic Fiber	Some fiber in Longevity Mix	✓Dedicated prebiotic blend
Third-Party Testing	Every batch tested, COAs published	Third-party tested
Price (Monthly)	$72 (Longevity Mix) or $265 (full stack)	✓$49.99/month (subscription)
Omega-3 Support	✓Dedicated high-quality Omega-3 product	Algae-based Omega-3 in some products
Multivitamin Coverage	✓24 essential nutrients at clinical doses	Not included
Scientific Backing	✓Based on $4M+ biological age research	Strain-specific clinical studies
Capsule Design	Standard capsules	✓2-in-1 nested capsule (survives stomach acid)
Sustainability	Standard packaging	✓Carbon-neutral, recyclable packaging

Strengths of Each

Blueprint Strengths

✓Comprehensive longevity stack covering multiple health areas
✓NMN for NAD+ support - critical for anti-aging
✓Full multivitamin coverage with clinical doses
✓High-quality Omega-3 for brain and heart health
✓Based on Bryan Johnson's measured biological age results
✓Transparent dosing - no proprietary blends

Seed Strengths

✓24 probiotic strains specifically chosen for research backing
✓Innovative 2-in-1 capsule survives stomach acid
✓More affordable single-product option
✓Strong focus on gut-brain connection
✓Sustainable and eco-friendly packaging
✓Simpler daily routine (1 capsule)

Which Should You Choose?

Choose Blueprint if:

You want comprehensive longevity support, NAD+ optimization, and a full-spectrum supplement stack. You're focused on biological age reversal and want clinically-dosed nutrients across multiple health systems.

Choose Seed if:

Gut health is your primary focus. You want a specialized, research-backed probiotic with innovative delivery technology. You prefer a simpler, single-product routine.

Ready to Optimize for Longevity?

Try Bryan Johnson's Blueprint supplements and get $25 off your first order. Third-party tested with published certificates of analysis.

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Learn more:

Is Blueprint Worth It?Bryan Johnson Supplement List Best NMN Supplements FAQ

Other comparisons:

Blueprint vs AG1 Blueprint vs Athletic Greens Blueprint vs Seed Blueprint vs Ritual Blueprint vs Thorne Blueprint vs Momentous Blueprint vs Life Extension Blueprint vs Generic NMN